423.8K XNAS Volume
XNAS 25 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 1.61 per share. | 21 Mar 2025 | 9,243 | 157,626 (0%) | 0% | 1.6 | 14,881 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 07 Mar 2025 | 6,332 | 148,383 (0%) | 0% | 2.3 | 14,880 | Common Stock |
| Jennifer S. Buell | Director | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 07 Mar 2025 | 409 | 15,646 (0%) | 0% | 2.3 | 961 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.32 per share. | 21 Feb 2025 | 4,483 | 142,051 (0%) | 0% | 3.3 | 14,884 | Common Stock |
| Jennifer S. Buell | Director | Grant, award, or other acquisition of securities at price $ 3.32 per share. | 21 Feb 2025 | 626 | 15,318 (0%) | 0% | 3.3 | 2,078 | Common Stock |
| Jennifer S. Buell | Director | Grant, award, or other acquisition of securities at price $ 3.32 per share. | 21 Feb 2025 | 545 | 15,237 (0%) | 0% | 3.3 | 1,809 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.50 per share. | 07 Feb 2025 | 4,251 | 137,568 (0%) | 0% | 3.5 | 14,879 | Common Stock |
| Jennifer S. Buell | Director | Grant, award, or other acquisition of securities at price $ 3.50 per share. | 07 Feb 2025 | 516 | 14,692 (0%) | 0% | 3.5 | 1,806 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.57 per share. | 24 Jan 2025 | 4,169 | 133,317 (0%) | 0% | 3.6 | 14,883 | Common Stock |
| Jennifer S. Buell | Director | Grant, award, or other acquisition of securities at price $ 3.57 per share. | 24 Jan 2025 | 776 | 14,446 (0%) | 0% | 3.6 | 2,770 | Common Stock |
| Jennifer S. Buell | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.57 per share. | 24 Jan 2025 | 270 | 14,176 (0%) | 0% | 3.6 | 964 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.12 per share. | 10 Jan 2025 | 4,777 | 129,148 (0%) | 0% | 3.1 | 14,904 | Common Stock |
| Wright Timothy R. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 2,532 | 14,204 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 6,416 | 16,206 | - | - | Deferred Stock Units | |
| H. Garo Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 2.75 per share. | 27 Dec 2024 | 5,931 | 124,371 (0%) | 0% | 2.7 | 16,310 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.05 per share. | 13 Dec 2024 | 5,347 | 118,440 (0%) | 0% | 3.0 | 16,308 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 3.42 per share. | 29 Nov 2024 | 4,769 | 113,093 (0%) | 0% | 3.4 | 16,310 | Common Stock |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2024 | 10,000 | 10,000 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2024 | 600,000 | 600,000 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 2.72 per share. | 14 Nov 2024 | 5,997 | 108,324 (0%) | 0% | 2.7 | 16,312 | Common Stock |
| Jennifer S. Buell | Director, Chairman Executive Council | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2024 | 300,000 | 300,000 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2024 | 50,000 | 50,000 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 4.05 per share. | 01 Nov 2024 | 4,207 | 102,327 (0%) | 0% | 4.0 | 17,038 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 4.62 per share. | 18 Oct 2024 | 3,530 | 98,300 (0%) | 0% | 4.6 | 16,309 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 4.87 per share. | 04 Oct 2024 | 3,349 | 94,770 (0%) | 0% | 4.9 | 16,310 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2024 | 3,423 | 19,500 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2024 | 1,252 | 11,671 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2024 | 3,172 | 9,790 | - | - | Deferred Stock Units | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 5.84 per share. | 20 Sep 2024 | 2,793 | 91,421 (0%) | 0% | 5.8 | 16,311 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 4.95 per share. | 06 Sep 2024 | 3,295 | 88,628 (0%) | 0% | 4.9 | 16,310 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 5.47 per share. | 23 Aug 2024 | 2,982 | 85,333 (0%) | 0% | 5.5 | 16,312 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 5.09 per share. | 09 Aug 2024 | 3,204 | 82,351 (0%) | 0% | 5.1 | 16,308 | Common Stock |
| Thomas L. Harrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2024 | 7,500 | 7,500 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 6.56 per share. | 26 Jul 2024 | 2,486 | 79,147 (0%) | 0% | 6.6 | 16,308 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 15.60 per share. | 12 Jul 2024 | 1,046 | 76,661 (0%) | 0% | 15.6 | 16,318 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2024 | 2,121 | 16,077 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2024 | 776 | 10,418 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2024 | 1,827 | 6,617 | - | - | Deferred Stock Units | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 16.75 per share. | 28 Jun 2024 | 973 | 75,615 (0%) | 0% | 16.8 | 16,298 | Common Stock |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 10,642 | 10,642 | - | - | Stock Option | |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 3,125 | 3,125 | - | - | Stock Option | |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 6,250 | 6,250 | - | - | Stock Option | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 750 | 750 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 108,000 | 108,000 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 65,651 | 65,651 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 15.46 per share. | 11 Jun 2024 | 1,055 | 74,642 (0%) | 0% | 15.5 | 16,310 | Common Stock |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 750 | 750 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 37,907 | 37,907 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 10,000 | 10,000 | - | - | Stock Option | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 15.69 per share. | 31 May 2024 | 1,040 | 73,587 (0%) | 0% | 15.7 | 16,318 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 10.86 per share. | 17 May 2024 | 1,502 | 72,547 (0%) | 0% | 10.9 | 16,312 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 13.07 per share. | 03 May 2024 | 1,248 | 71,045 (0%) | 0% | 13.1 | 16,311 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 5.31 per share. | 19 Apr 2024 | 3,080 | 69,797 (0%) | 0% | 5.3 | 16,355 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.50 per share. | 05 Apr 2024 | 32,697 | 1,335,325 (0%) | 0% | 0.5 | 16,349 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2024 | 38,635 | 279,121 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2024 | 14,134 | 192,858 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2024 | 32,039 | 95,791 | - | - | Deferred Stock Units | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.55 per share. | 22 Mar 2024 | 27,163 | 1,302,628 (0%) | 0% | 0.6 | 14,940 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.67 per share. | 08 Mar 2024 | 22,136 | 1,275,465 (0%) | 0% | 0.7 | 14,831 | Common Stock |
| Garo Armen H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.68 per share. | 23 Feb 2024 | 21,815 | 1,253,329 (0%) | 0% | 0.7 | 14,834 | Common Stock |
| Garo Armen H. | Director, See Remarks | Purchase of securities on an exchange or from another person at price $ 0.65 per share. | 15 Feb 2024 | 500,000 | 625,969 (0%) | 0% | 0.6 | 324,050 | Common Stock |
| Garo Armen H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.75 per share. | 09 Feb 2024 | 19,778 | 1,231,514 (0%) | 0% | 0.8 | 14,834 | Common Stock |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 15,000 | 15,000 | - | - | Stock Option | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 5,000 | 5,000 | - | - | Stock Option | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 5,000 | 5,000 | - | - | Stock Option | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 7,500 | 7,500 | - | - | Stock Option | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 5,000 | 5,000 | - | - | Stock Option | |
| Armen H. Garo | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.66 per share. | 26 Jan 2024 | 22,475 | 1,211,736 (0%) | 0% | 0.7 | 14,834 | Common Stock |
| Garo Armen H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.64 per share. | 12 Jan 2024 | 23,177 | 1,439,261 (1%) | 0% | 0.6 | 14,833 | Common Stock |
| Hirsch Susan B. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 25,671 | 63,751 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 30,956 | 240,485 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 11,325 | 178,723 | - | - | Deferred Stock Units | |
| B. Hirsch Susan | Director | 31 Dec 2023 | 5,000 | 113,725 (0%) | 0% | 0.7 | 3,350 | Common Stock | |
| Timothy R. Wright | Director | 31 Dec 2023 | 5,000 | 55,391 (0%) | 0% | 0.9 | 4,400 | Common Stock | |
| Susan B. Hirsch | Director | 31 Dec 2023 | 5,000 | 118,725 (0%) | 0% | 0.8 | 3,750 | Common Stock | |
| Garo Armen H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.83 per share. | 29 Dec 2023 | 23,453 | 1,416,084 (1%) | 0% | 0.8 | 19,466 | Common Stock |
| Garo Armen H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.69 per share. | 15 Dec 2023 | 23,453 | 1,396,538 (1%) | 0% | 0.7 | 16,183 | Common Stock |
| Armen Garo H. | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.78 per share. | 01 Dec 2023 | 20,727 | 1,373,085 (0%) | 0% | 0.8 | 16,167 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jul 2023 | 16,018 | 191,528 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jul 2023 | 5,860 | 160,812 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jul 2023 | 13,283 | 23,153 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2023 | 11,901 | 175,510 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2023 | 4,354 | 154,951 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2023 | 9,869 | 9,869 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2023 | 100,000 | 100,000 | - | - | Stock Option | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2023 | 100,000 | 100,000 | - | - | Stock Option | |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 2.45 per share. | 05 Jan 2023 | 31,294 | 153,937 (0%) | 0% | 2.4 | 76,670 | Common Stock |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 162,916 | 162,916 | - | - | Stock Option | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.45 per share. | 05 Jan 2023 | 241,383 | 1,249,167 (0%) | 0% | 2.4 | 591,388 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 2,400,000 | 2,400,000 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 200,000 | 200,000 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 2.45 per share. | 05 Jan 2023 | 109,381 | 272,384 (0%) | 0% | 2.4 | 267,983 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 9,893 | 163,608 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 3,619 | 150,597 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 2.59 per share. | 03 Jan 2023 | 7,239 | 108,725 (0%) | 0% | 2.6 | 18,749 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2022 | 9,862 | 153,714 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2022 | 3,608 | 146,977 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2022 | 10,102 | 239,944 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 2.60 per share. | 03 Oct 2022 | 7,216 | 101,486 (0%) | 0% | 2.6 | 18,747 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 13,854 | 143,852 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 5,068 | 143,369 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 14,192 | 229,841 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 1.85 per share. | 01 Jul 2022 | 10,138 | 94,270 (0%) | 0% | 1.8 | 18,755 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 9,307 | 129,997 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 3,405 | 138,300 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 9,534 | 215,648 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 150,000 | 150,000 | - | - | Stock Option | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 2.51 per share. | 02 Feb 2022 | 29,587 | 122,643 (0%) | 0% | 2.5 | 74,263 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.51 per share. | 02 Feb 2022 | 237,011 | 1,007,784 (0%) | 0% | 2.5 | 594,898 | Common Stock |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 2.51 per share. | 02 Feb 2022 | 101,682 | 163,003 (0%) | 0% | 2.5 | 255,222 | Common Stock |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2022 | 100,000 | 100,000 | - | - | Stock Option | |
| Steven J. O'Day | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2022 | 100,000 | 0 | - | - | Restricted Stock Units | |
| Steven J. O'Day | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.06 per share. | 04 Jan 2022 | 38,679 | 61,321 (0%) | 0% | 3.1 | 118,346 | Common Stock |
| Steven J. O'Day | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2022 | 100,000 | 100,000 (0%) | 0% | - | Common Stock | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 6,391 | 120,689 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 2,338 | 134,895 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 6,547 | 206,113 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 4.01 per share. | 03 Jan 2022 | 4,677 | 21,571 (0%) | 0% | 4.0 | 18,755 | Common Stock |
| Christine M. Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2022 | 1,900,000 | 1,900,000 | - | - | Stock Option (Right to Buy) | |
| Steven J. O'Day | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2022 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 4,451 | 114,297 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 1,628 | 132,556 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 4,559 | 199,566 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 5.76 per share. | 01 Oct 2021 | 3,257 | 16,894 (0%) | 0% | 5.8 | 18,760 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.36 per share. | 13 Sep 2021 | 119,178 | 852,880 (0%) | 0% | 3.4 | 400,438 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Sale of securities on an exchange or to another person at price $ 6.50 per share. | 13 Sep 2021 | 82,107 | 770,773 (0%) | 0% | 6.5 | 533,696 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2021 | 119,178 | 0 | - | - | Stock Option, right to buy | |
| Christine Klaskin | PFO & PAO | Sale of securities on an exchange or to another person at price $ 6.50 per share. | 10 Sep 2021 | 11,120 | 93,056 (0%) | 0% | 6.5 | 72,280 | Common Stock |
| Christine Klaskin | PFO & PAO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Sep 2021 | 16,563 | 0 | - | - | Stock Option, right to buy | |
| Christine Klaskin | PFO & PAO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.36 per share. | 10 Sep 2021 | 16,563 | 104,176 (0%) | 0% | 3.4 | 55,652 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 5.26 per share. | 18 Jun 2021 | 2,812 | 610,023 (0%) | 0% | 5.3 | 14,791 | Common Stock |
| Ulf Wiinberg | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 16,853 | 99,063 (0%) | 0% | - | Common Stock | |
| Timothy R. Wright | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 16,853 | 50,391 (0%) | 0% | - | Common Stock | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 20,501 | 20,501 | - | - | Stock Option | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 12,000 | 12,000 | - | - | Restricted Stock Unit | |
| Brian J. Corvese | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 16,000 | 16,000 | - | - | Restricted Stock Unit | |
| Brian J. Corvese | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 22,471 | 92,085 (0%) | 0% | - | Common Stock | |
| Allison M. Jeynes-Ellis | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 16,853 | 66,176 (0%) | 0% | - | Common Stock | |
| Christine Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 50,000 | 50,000 | - | - | Stock Option | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 6,707 | 109,846 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,453 | 130,928 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 6,870 | 195,006 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| Adam Krauss | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 175,000 | 175,000 | - | - | Stock Option, (Right to buy) | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.03 per share. | 04 Jun 2021 | 3,670 | 607,211 (0%) | 0% | 4.0 | 14,790 | Common Stock |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 4.19 per share. | 21 May 2021 | 3,530 | 603,541 (0%) | 0% | 4.2 | 14,791 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.07 per share. | 07 May 2021 | 4,817 | 600,011 (0%) | 0% | 3.1 | 14,788 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.05 per share. | 23 Apr 2021 | 4,849 | 595,194 (0%) | 0% | 3.0 | 14,789 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.78 per share. | 09 Apr 2021 | 4,645 | 590,345 (0%) | 0% | 2.8 | 12,936 | Common Stock |
| Christine Klaskin | PFO & PAO | Grant, award, or other acquisition of securities at price $ 2.87 per share. | 02 Apr 2021 | 24,278 | 88,611 (0%) | 0% | 2.9 | 69,678 | Common Stock |
| Garo H. Armen | Director, Chairman & CEO | Grant, award, or other acquisition of securities at price $ 2.87 per share. | 02 Apr 2021 | 135,778 | 585,700 (0%) | 0% | 2.9 | 389,683 | Common Stock |
| Jennifer Buell | President & COO | Grant, award, or other acquisition of securities at price $ 2.87 per share. | 02 Apr 2021 | 80,838 | 116,494 (0%) | 0% | 2.9 | 232,005 | Common Stock |
| Paul N. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 5,092 | 5,092 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 6,959 | 110,098 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 2,546 | 128,474 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 7,129 | 188,135 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 5,092 | 8,729 (0%) | 0% | - | Common Stock | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.85 per share. | 26 Mar 2021 | 4,177 | 449,922 (0%) | 0% | 2.8 | 11,904 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.31 per share. | 12 Mar 2021 | 3,428 | 445,745 (0%) | 0% | 3.3 | 11,347 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.00 per share. | 26 Feb 2021 | 2,836 | 442,317 (0%) | 0% | 4 | 11,344 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.64 per share. | 12 Feb 2021 | 2,445 | 439,481 (0%) | 0% | 4.6 | 11,345 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.68 per share. | 29 Jan 2021 | 3,083 | 437,036 (0%) | 0% | 3.7 | 11,345 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.35 per share. | 15 Jan 2021 | 3,386 | 433,953 (0%) | 0% | 3.3 | 11,343 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 5,896 | 96,179 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 2,149 | 125,928 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 5,621 | 181,005 | - | - | Deferred Stock Units | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 3.78 per share. | 04 Jan 2021 | 3,637 | 3,637 (0%) | 0% | 3.8 | 13,748 | Common Stock |
| Christine Klaskin | PFO and PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 50,000 | 50,000 | - | - | Stock Option (Right to buy) | |
| Paul N. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 1,900,000 | 1,900,000 | - | - | Stock Option (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.55 per share. | 17 Dec 2020 | 4,163 | 421,845 (0%) | 0% | 3.6 | 14,779 | Common Stock |
| Brian Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Jennifer Buell | COO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 900,000 | 900,000 | - | - | Stock Option (Right to buy) | |
| Evan Kearns | VP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 150,000 | 150,000 | - | - | Stock Option (Right to buy) | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Adam Krauss | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 50,000 | 50,000 | - | - | Stock Option, (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 04 Dec 2020 | 31,100 | 704,046 (0%) | 0% | 0 | Common Stock | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.33 per share. | 04 Dec 2020 | 4,437 | 417,682 (0%) | 0% | 3.3 | 14,775 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 04 Dec 2020 | 62,200 | 735,146 (0%) | 0% | 0 | Common Stock | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.65 per share. | 20 Nov 2020 | 4,049 | 412,645 (0%) | 0% | 3.7 | 14,779 | Common Stock |
| Garo H Armen | Director | Grant, award, or other acquisition of securities at price $ 3.82 per share. | 06 Nov 2020 | 3,869 | 343,496 (0%) | 0% | 3.8 | 14,780 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.94 per share. | 23 Oct 2020 | 3,751 | 339,627 (0%) | 0% | 3.9 | 14,779 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.35 per share. | 09 Oct 2020 | 3,397 | 335,876 (0%) | 0% | 4.4 | 14,777 | Common Stock |
| Susan B. Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Oct 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 6,464 | 90,282 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 2,049 | 123,778 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 5,360 | 175,384 | - | - | Deferred Stock Units | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.02 per share. | 25 Sep 2020 | 3,676 | 332,479 (0%) | 0% | 4.0 | 14,778 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.99 per share. | 11 Sep 2020 | 2,962 | 328,803 (0%) | 0% | 5.0 | 14,780 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.28 per share. | 28 Aug 2020 | 3,452 | 325,841 (0%) | 0% | 4.3 | 14,775 | Common Stock |
| Paul N. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2020 | 11,786 | 11,786 | - | - | Restricted Stock Unit | |
| Paul N. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2020 | 100,000 | 100,000 | - | - | Stock Option (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.71 per share. | 14 Aug 2020 | 3,984 | 322,389 (0%) | 0% | 3.7 | 14,781 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.04 per share. | 31 Jul 2020 | 4,861 | 318,405 (0%) | 0% | 3.0 | 14,777 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.60 per share. | 17 Jul 2020 | 4,105 | 313,544 (0%) | 0% | 3.6 | 14,778 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 4.02 per share. | 02 Jul 2020 | 3,676 | 309,439 (0%) | 0% | 4.0 | 14,778 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 8,398 | 83,817 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 2,662 | 121,729 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 6,964 | 170,023 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 82,210 (0%) | 0% | - | Common Stock | |
| Ulf Wiinberg | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 0 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 53,876 (0%) | 0% | - | Common Stock | |
| Timothy R. Wright | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 0 | - | - | Restricted Stock Unit | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.83 per share. | 19 Jun 2020 | 3,859 | 305,763 (0%) | 0% | 3.8 | 14,780 | Common Stock |
| Brian Corvese | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 21,118 | 0 | - | - | Restricted Stock Unit | |
| Brian Corvese | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 21,118 | 69,614 (0%) | 0% | - | Common Stock | |
| Allison M. Jeynes-Ellis | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 49,323 (0%) | 0% | - | Common Stock | |
| Allison M. Jeynes-Ellis | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2020 | 20,338 | 0 | - | - | Restricted Stock Unit | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 16,853 | 37,191 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 2,500 | 2,500 | - | - | Stock Option (Right to buy) | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 16,853 | 37,191 | - | - | Restricted Stock Unit | |
| Brian Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 2,500 | 2,500 | - | - | Stock Option (Right to buy) | |
| Brian Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 22,471 | 49,589 | - | - | Restricted Stock Unit | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 2,500 | 2,500 | - | - | Stock Option (Right to buy) | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2020 | 16,853 | 37,191 | - | - | Restricted Stock Unit | |
| Christine Klaskin | PFO and PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 12,500 | 12,500 | - | - | Stock Option (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 58,333 | 58,333 | - | - | Stock Option (Right to buy) | |
| Jennifer Buell | COO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 10,000 | 10,000 | - | - | Stock Option (Right to buy) | |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 3.85 per share. | 05 Jun 2020 | 3,838 | 301,904 (0%) | 0% | 3.8 | 14,776 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.50 per share. | 22 May 2020 | 5,911 | 298,066 (0%) | 0% | 2.5 | 14,778 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 2.56 per share. | 12 May 2020 | 159,000 | 1,051,155 (0%) | 0% | 2.6 | 407,040 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 2.29 per share. | 12 May 2020 | 600,000 | 292,155 (0%) | 0% | 2.3 | 1,374,000 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 2.29 per share. | 12 May 2020 | 159,000 | 892,155 (0%) | 0% | 2.3 | 364,110 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.53 per share. | 08 May 2020 | 5,842 | 892,155 (0%) | 0% | 2.5 | 14,780 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.50 per share. | 10 Apr 2020 | 5,911 | 1,106,986 (0%) | 0% | 2.5 | 14,778 | Common Stock |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 8,009 | 75,419 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 2,539 | 119,066 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 6,641 | 163,059 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 5,667 | 67,410 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 2,285 | 116,526 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 5,850 | 156,417 | - | - | Deferred Stock Units | |
| Christine M. Klaskin | PFO and PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 85,000 | 85,000 | - | - | Stock Option (Right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to buy) | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to buy) | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 1,500,000 | 1,500,000 | - | - | Stock Option (Right to buy) | |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to buy) | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to buy) | |
| Jennifer S. Buell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 500,000 | 500,000 | - | - | Stock Option (Right to buy) | |
| Evan Kearns | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 300,000 | 300,000 | - | - | Stock Option (Right to buy) | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to buy) | |
| Garo H. Armen | Director, Chairman and CEO | Other type of transaction at price $ 3.88 per share. | 17 Dec 2019 | 66,000 | 1,362,433 (0%) | 0% | 3.9 | 256,080 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Other type of transaction at price $ 3.88 per share. | 17 Dec 2019 | 66,000 | 1,296,433 (0%) | 0% | 3.9 | 256,080 | Common Stock |
| Garo H. Armen | Director, Chairman and CEO | Other type of transaction at price $ 3.77 per share. | 17 Dec 2019 | 195,358 | 1,101,075 (0%) | 0% | 3.8 | 736,500 | Common Stock |
| Christine M. Klaskin | PFO and PAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2019 | 4,537 | 4,537 | - | - | Stock Option (Right to buy) | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2019 | 87,500 | 87,500 | - | - | Stock Option (Right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2019 | 7,107 | 61,743 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2019 | 2,865 | 114,241 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2019 | 7,336 | 150,567 | - | - | Deferred Stock Units | |
| Christine M. Klaskin | Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 14,667 | 14,667 | - | - | Stock Option (Right to buy) | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 250,000 | 250,000 | - | - | Stock Option (Right to buy) | |
| Jennifer S. Buell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 84,000 | 84,000 | - | - | Stock Option (Right to buy) | |
| Alex Duncan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to buy) | |
| Evan Kearns | VP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 18,333 | 18,333 | - | - | Stock Option (Right to buy) | |
| Christian Cortis | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2019 | 18,333 | 18,333 | - | - | Stock Option (Right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2019 | 6,961 | 54,636 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2019 | 2,806 | 111,375 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2019 | 7,185 | 143,230 | - | - | Deferred Stock Units | |
| Christine M. Klaskin | V.P. Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 75,000 | 75,000 | - | - | Stock Option(right to buy) | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 100,000 | 100,000 | - | - | Stock Option, Right to buy | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 20,338 | 20,338 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 2,500 | 2,500 | - | - | Stock Option, Right to buy | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 20,338 | 20,338 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 100,000 | 102,500 | - | - | Stock Option, Right to buy | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 1,665,000 | 1,665,000 | - | - | Stock Option, Right to buy | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 42,500 | 42,500 | - | - | Stock Option (Right to buy) | |
| Garo H. Armen | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 647,682 | 647,682 | - | - | Restricted Stock Unit | |
| Garo H. Armen | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 2.79 per share. | 19 Jun 2019 | 5,296 | 1,112,282 (0%) | 0% | 2.8 | 14,776 | Common Stock |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 27,118 | 27,118 | - | - | Restricted Stock Unit | |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 100,000 | 102,500 | - | - | Stock Option, Right to buy | |
| Brian J. Corvese | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 2,500 | 2,500 | - | - | Stock Option, Right to buy | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 2,500 | 2,500 | - | - | Stock Option, Right to buy | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 100,000 | 102,500 | - | - | Stock Option, Right to buy | |
| Jennifer S. Buell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 300,000 | 300,000 | - | - | Stock Option (right to buy) | |
| Alex Duncan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 210,000 | 210,000 | - | - | Stock Option(right to buy) | |
| Evan Kearns | V.P. and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 200,000 | 200,000 | - | - | Stock Option(right to buy) | |
| Christian Cortis | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 135,000 | 135,000 | - | - | Stock Option(right to buy) | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 50,000 | 50,000 | - | - | Stock Option, Right to buy | |
| Allison M. Jeynes-Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2019 | 20,338 | 20,338 | - | - | Restricted Stock Unit | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2019 | 6,129 | 47,674 | - | - | Deferred Stock Units | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2019 | 2,471 | 108,568 | - | - | Deferred Stock Units | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2019 | 6,327 | 136,045 | - | - | Deferred Stock Units | |
| Ulf Wiinberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2019 | 7,940 | 7,940 | - | - | Deferred Shares | |
| Timothy R. Wright | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2019 | 3,382 | 3,382 | - | - | Deferred Shares | |
| Wadih Jordan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2019 | 8,234 | 8,234 | - | - | Deferred Shares | |
| Jennifer Buell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2018 | 130,000 | 130,000 | - | - | Stock Option (right to buy) | |
| Allison M. Jeynes-Ellis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2018 | 28,985 | 28,985 (0%) | 0% | 0 | Common Stock | |
| Allison M. Jeynes-Ellis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2018 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2018 | 8,416 | 8,416 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2018 | 3,585 | 3,584 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2018 | 8,728 | 8,727 | - | - | Deferred Shares | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jul 2018 | 4,914 | 4,913 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jul 2018 | 2,093 | 2,092 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jul 2018 | 5,096 | 5,095 | - | - | Deferred Shares | |
| Christine Klaskin | VP Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 83,150 | 83,150 | - | - | Stock Option, right to buy | |
| Karen Valentine | Chief Legal Officer and GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 173,150 | 173,150 | - | - | Stock Options, right to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 15,957 | 15,957 | - | - | Restricted Stock Unit | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 37,500 | 37,500 | - | - | Stock Option, right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 15,957 | 15,957 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 37,500 | 37,500 | - | - | Stock Option, right to buy | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 935,200 | 935,200 | - | - | Stock Option, right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 37,500 | 37,500 | - | - | Stock Option, right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 21,276 | 21,276 | - | - | Restricted Stock Unit | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 37,500 | 37,500 | - | - | Common Stock | |
| Ozer Baysal | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 165,000 | 165,000 | - | - | Stock Option, right to buy | |
| Jennifer Buell | Chief Communications Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 150,000 | 150,000 | - | - | Common Stock, right to buy | |
| Alex Duncan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2018 | 165,000 | 165,000 | - | - | Common Stock | |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 3.77 per share. | 06 Apr 2018 | 195,358 | 1,035,075 (0%) | 0% | 3.8 | 736,500 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 4.82 per share. | 06 Apr 2018 | 140,974 | 1,221,433 (1%) | 0% | 4.8 | 679,495 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 2.16 per share. | 06 Apr 2018 | 300,000 | 1,521,433 (1%) | 0% | 2.2 | 648,000 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 2.16 per share. | 06 Apr 2018 | 225,000 | 1,296,433 (1%) | 0% | 2.2 | 486,000 | Common Stock |
| Garo H Armen | Director, Chairman and CEO | Other type of transaction at price $ 3.88 per share. | 06 Apr 2018 | 66,000 | 1,230,433 (0%) | 0% | 3.9 | 256,080 | Common Stock |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2018 | 3,867 | 3,866 | - | - | Deferred Shares | |
| Ulf Wiinberg | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 15,915 | 0 | - | - | Restricted Stock Units | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2018 | 3,729 | 3,728 | - | - | Deferred Shares | |
| Ulf Wiinberg | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 15,915 | 45,915 (0%) | 0% | 0 | Common Stock | |
| Timothy R. Wright | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 15,915 | 17,581 (0%) | 0% | 0 | Common Stock | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2018 | 1,588 | 1,588 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 15,915 | 0 | - | - | Restricted Stock Units | |
| Brian Corvese | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 21,220 | 21,220 (0%) | 0% | 0 | Common Stock | |
| Brian Corvese | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2018 | 21,220 | 0 | - | - | Restricted Stock Units | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2018 | 18,533 | 18,533 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2018 | 37,500 | 37,500 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2018 | 10,000 | 10,000 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2018 | 18,533 | 18,533 | - | - | Stock Option, Right to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 4,340 | 4,339 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 1,945 | 1,944 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 5,272 | 5,271 | - | - | Deferred Shares | |
| Garo H Armen | Chairman and CEO | Other type of transaction at price $ 3.96 per share. | 30 Nov 2017 | 300,000 | 1,290,441 (1%) | 0% | 4.0 | 1,188,000 | Common Stock |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 3.61 per share. | 27 Oct 2017 | 40,388 | 1,590,441 (1%) | 0% | 3.6 | 145,853 | Common Stock |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 3.51 per share. | 27 Oct 2017 | 59,612 | 1,550,053 (1%) | 0% | 3.5 | 209,262 | Common Stock |
| Christine Klaskin | VP, Finance | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 09 Oct 2017 | 5,610 | 64,333 (0%) | 0% | 3.5 | 19,418 | Common Stock |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 10,431 | 69,943 (0%) | 0% | 3.6 | 37,447 | Common Stock |
| Karen Valentine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 09 Oct 2017 | 8,358 | 101,521 (0%) | 0% | 3.5 | 28,921 | Common Stock |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 24,824 | 109,879 (0%) | 0% | 3.6 | 89,118 | Common Stock |
| Garo H Armen | CEO and Chairman of the Board | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 71,966 | 1,362,407 (1%) | 0% | 3.6 | 258,358 | Common Stock |
| Ozer Baysal | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 13,080 | 62,502 (0%) | 0% | 3.6 | 46,957 | Common Stock |
| Ozer Baysal | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 09 Oct 2017 | 3,712 | 58,790 (0%) | 0% | 3.5 | 12,846 | Common Stock |
| Jennifer Buell | Chief Communications Officer | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 09 Oct 2017 | 3,511 | 35,656 (0%) | 0% | 3.5 | 12,152 | Common Stock |
| Jennifer Buell | Chief Communications Officer | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 10,431 | 39,167 (0%) | 0% | 3.6 | 37,447 | Common Stock |
| Alex Duncan | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 09 Oct 2017 | 6,546 | 21,026 (0%) | 0% | 3.5 | 22,651 | Common Stock |
| Alex Duncan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 3.59 per share. | 09 Oct 2017 | 13,423 | 27,572 (0%) | 0% | 3.6 | 48,189 | Common Stock |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2017 | 4,091 | 4,090 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2017 | 1,742 | 1,742 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2017 | 4,242 | 4,242 | - | - | Deferred Shares | |
| Jennifer Buell | VP Research & External Affairs | Grant, award, or other acquisition of securities at price $ 3.72 per share. | 03 Sep 2017 | 4,375 | 28,736 (0%) | 0% | 3.7 | 16,275 | Common Stock |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option, Right to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option, Roght to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 4,710 | 4,709 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 2,500 | 2,500 | - | - | Stock Option, Right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 50,000 | 50,000 | - | - | Stok Option, Right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 2,006 | 2,006 | - | - | Deferred Shares | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 2,500 | 2,500 | - | - | Stock Option, Right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option, Right to buy | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 2,500 | 2,500 | - | - | Stock Optoin, Right to buy | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 4,187 | 4,186 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option, Right to buy | |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 3.39 per share. | 19 Apr 2017 | 10,429 | 63,245 (0%) | 0% | 3.4 | 35,354 | Common Stock |
| Christine Klaskin | VP, Finance | Sale or transfer of securities back to the company at price $ 3.39 per share. | 19 Apr 2017 | 3,733 | 59,512 (0%) | 0% | 3.4 | 12,655 | Common Stock |
| Karen Valentine | Chief Legal Officer | Sale or transfer of securities back to the company at price $ 3.39 per share. | 19 Apr 2017 | 8,055 | 85,055 (0%) | 0% | 3.4 | 27,306 | Common Stock |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 3.39 per share. | 19 Apr 2017 | 24,822 | 93,110 (0%) | 0% | 3.4 | 84,147 | Common Stock |
| Garo H Armen | Chairman & CEO | Grant, award, or other acquisition of securities at price $ 3.39 per share. | 19 Apr 2017 | 71,964 | 1,490,441 (1%) | 0% | 3.4 | 243,958 | Common Stock |
| Ozer Baysal | Chief Business Officer | Sale or transfer of securities back to the company at price $ 3.39 per share. | 19 Apr 2017 | 3,539 | 49,422 (0%) | 0% | 3.4 | 11,997 | Common Stock |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 3.39 per share. | 19 Apr 2017 | 13,078 | 52,961 (0%) | 0% | 3.4 | 44,334 | Common Stock |
| Garo H Armen | Director, Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 3.37 per share. | 10 Apr 2017 | 70,544 | 1,389,021 (1%) | 0% | 3.4 | 237,465 | Common Stock |
| Garo H Armen | Director, Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 3.29 per share. | 10 Apr 2017 | 29,456 | 1,418,477 (1%) | 0% | 3.3 | 97,055 | Common Stock |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2017 | 3,406 | 3,406 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2017 | 1,587 | 1,586 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2017 | 3,716 | 3,715 | - | - | Deferred Shares | |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 72,500 | 72,500 | - | - | Stock Option, Right to Buy | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 162,500 | 162,500 | - | - | Stock Option, Right to Buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 15,915 | 15,915 | - | - | Restricted Stock Unit | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 15,915 | 15,915 | - | - | Restricted Stock Unit | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 853,000 | 853,000 | - | - | Stock Option, Right to Buy | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 647,000 | 647,000 | - | - | Restricted Stock Unit | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 21,220 | 21,220 | - | - | Restricted Stock Unit | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 75,000 | 75,000 | - | - | Stock Option, Right to Buy | |
| Robert Benjamin Stein | President R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 100,000 | 100,000 | - | - | Stock Option, Right to Buy | |
| Jean-Marie Cuillerot | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2017 | 232,500 | 232,500 | - | - | Stock Option, Right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Mar 2017 | 4,166 | 4,166 | - | - | Stock Option, Right to Buy | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 8,800 | 8,800 | - | - | Stock Option, Right to Buy | |
| Jean-Marie Cuillerot | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jan 2017 | 100,000 | 100,000 | - | - | Stock Option, Right to Buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2017 | 4,166 | 4,166 | - | - | Stock Option, right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 1,281 | 1,280 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 2,998 | 2,998 | - | - | Deferred Shares | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 4.16 per share. | 03 Jan 2017 | 6,250 | 39,883 (0%) | 0% | 4.2 | 26,000 | Common Stock |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 21 Dec 2016 | 152,405 | 1,318,477 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 21 Dec 2016 | 78,001 | 1,470,882 | - | - | Common Stock | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2016 | 2,568 | 2,567 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2016 | 1,097 | 1,096 | - | - | Deferred Shares | |
| Garo H Armen | Director, Chairman & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Sep 2016 | 53,037 | 53,037 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Sep 2016 | 13,711 | 13,711 | - | - | Stock Option, right to buy | |
| Christine Klaskin | VP Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Sep 2016 | 7,551 | 7,551 | - | - | Stock Option, right to buy | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Sep 2016 | 2,083 | 2,083 | - | - | Stock Option, right to buy | |
| Ulf Wiinberg | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Sep 2016 | 30,000 | 30,000 | - | - | Common Stock | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2016 | 3,777 | 3,776 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2016 | 1,613 | 1,612 | - | - | Deferred Shares | |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 29 Jun 2016 | 152,405 | 1,548,883 | - | - | Common Stock | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Shahzad Malik | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2016 | 35,000 | 35,000 | - | - | Stock Option, right to buy | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 132,500 | 132,500 | - | - | Restricted Stock Unit | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 555,000 | 555,000 | - | - | Stock Option, right to buy | |
| Christine Klaskin | VP Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 13,500 | 13,500 | - | - | Restricted Stock Unit | |
| Christine Klaskin | VP Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 30,000 | 30,000 | - | - | Stock Option, right to buy | |
| C. Evan Ballantyne | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 75,000 | 75,000 | - | - | Stock Option, right to buy | |
| C. Evan Ballantyne | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 14,000 | 14,000 | - | - | Restricted Stock Unit | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 140,000 | 140,000 | - | - | Stock Option, right to buy | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 27,500 | 27,500 | - | - | Restricted Stock Unit | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 13,500 | 13,500 | - | - | Restricted Stock Unit | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 40,000 | 40,000 | - | - | stock Option, right to buy | |
| Robert Benjamin Stein | President R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 34,000 | 34,000 | - | - | Restricted Stock Unit | |
| Robert Benjamin Stein | President R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2016 | 250,000 | 250,000 | - | - | Stock Option, right to buy | |
| Ulf Wiinberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2016 | 45,000 | 45,000 | - | - | Stock Option, right to buy | |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2016 | 50,000 | 1,396,026 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2016 | 50,000 | 1,346,026 | - | - | Common Stock | |
| Ozer Baysal | Chief Business Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 May 2016 | 2,250 | 33,538 | - | - | Common Stock | |
| Garo H Armen | Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 71,964 | 1,423,192 | - | - | Common Stock | |
| Garo H Armen | Chairman and CEO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 26,714 | 1,396,478 | - | - | Common Stock | |
| Christine Klaskin | VP Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 10,429 | 55,369 | - | - | Common Stock | |
| Christine Klaskin | VP Finance | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 3,553 | 52,816 | - | - | Common Stock | |
| C. Evan Ballantyne | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 21,902 | 31,902 | - | - | Common Stock | |
| C. Evan Ballantyne | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 7,107 | 24,795 | - | - | Common Stock | |
| Karen Valentine | Chief Legal Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 8,068 | 68,288 | - | - | Common stock | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 24,822 | 76,356 | - | - | Common Stock | |
| Karen Valentine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 24,822 | 76,356 | - | - | Common Stock | |
| Karen Valentine | Chief Legal Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 8,068 | 68,288 | - | - | Common stock | |
| Ozer Baysal | Chief Business Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 3,545 | 33,633 | - | - | Common stock | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 13,078 | 37,178 | - | - | Common stock | |
| Robert Benjamin Stein | President R&D | Sale or transfer of securities back to the company at price $ 0.00 per share. | 26 Apr 2016 | 12,389 | 20,986 | - | - | Common Stock | |
| Robert Benjamin Stein | President R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Apr 2016 | 33,375 | 33,375 | - | - | Common Stock | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2016 | 1,019 | 1,018 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2016 | 409 | 409 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2016 | 3,347 | 3,347 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2016 | 1,455 | 1,455 | - | - | Deferred Shares | |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Mar 2016 | 200,000 | 1,251,228 | - | - | Common Stock | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 637 | 636 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 1,073 | 1,072 | - | - | Deferred Shares | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 6,250 | 21,850 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Dec 2015 | 44,435 | 1,388,369 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Dec 2015 | 89,917 | 1,298,452 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Dec 2015 | 85,224 | 1,213,228 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 28 Dec 2015 | 162,000 | 1,051,228 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 01 Oct 2015 | 83,697 | 1,493,304 | - | - | Common Stock | |
| Garo H Armen | Chairman & CEO | Other type of transaction at price $ 0.00 per share. | 01 Oct 2015 | 60,500 | 1,432,804 | - | - | Common Stock | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2015 | 394 | 393 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2015 | 663 | 662 | - | - | Deferred Shares | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Sep 2015 | 22,000 | 104,270 | - | - | Commmon Stock | |
| Garo H Armen | Chairman & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 Sep 2015 | 100,000 | 1,409,607 | - | - | Common Stock | |
| C. Evan Ballantyne | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 Sep 2015 | 10,000 | 10,000 | - | - | Commmon Stock | |
| Garo H Armen | Chairman & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jul 2015 | 36,000 | 36,000 | - | - | Stock Option, right to buy | |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jul 2015 | 5,250 | 5,250 | - | - | Stock Option, right to buy | |
| Karen Valentine | VP, General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jul 2015 | 12,000 | 12,000 | - | - | Stock Option, right to buy | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jul 2015 | 5,850 | 5,850 | - | - | Stock Option, right to buy | |
| Robert Benjamin Stein | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jul 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2015 | 411 | 410 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2015 | 692 | 691 | - | - | Deferred Shares | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Shalini Sharp | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Shahzad Malik | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| Brian Corvese | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2015 | 18,750 | 18,750 | - | - | Stock Option, right to buy | |
| C. Evan Ballantyne | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2015 | 150,000 | 150,000 | - | - | Stock Option, right to buy | |
| Shahzad Malik | None | Other type of transaction at price $ 0.00 per share. | 27 May 2015 | 1,587,302 | 1,587,302 | - | - | Common Stock | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2015 | 583 | 583 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2015 | 982 | 982 | - | - | Deferred Shares | |
| Garo H Armen | Chairman & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 10,000 | 10,000 | - | - | Stock Option, Right to Buy | |
| Garo H Armen | Chairman & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 168,000 | 168,000 | - | - | Stock Option, Right to Buy | |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 10,000 | 10,000 | - | - | Stock Option, Right to Buy | |
| Christine Klaskin | VP, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 24,500 | 24,500 | - | - | Stock Option, Right to Buy | |
| Karen Valentine | VP, General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 10,000 | 10,000 | - | - | Stock Option, Right to Buy | |
| Karen Valentine | VP, General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 56,000 | 56,000 | - | - | Stock Option, Right to Buy | |
| Ozer Baysal | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 27,300 | 27,300 | - | - | Stock Option, right to buy | |
| Robert Benjamin Stein | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2015 | 87,500 | 87,500 | - | - | Stock Option, Right to Buy | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 947 | 946 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 3,668 | 3,667 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 6,379 | 6,378 | - | - | Deferred Shares | |
| Ozer Baysal | CBO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 6,250 | 15,600 | - | - | Common Stock | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 930 | 929 | - | - | Deferred Shares | |
| Wadih Jordan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 3,601 | 3,601 | - | - | Deferred Shares | |
| Timothy R. Wright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 6,263 | 6,263 | - | - | Deferred Shares | |
| Tom Dechaene | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 975 | 975 | - | - | Deferred Shares |